diff --git a/external/builder/babel-plugin-pdfjs-preprocessor.mjs b/external/builder/babel-plugin-pdfjs-preprocessor.mjs
index f2610cf8c..d90613e84 100644
--- a/external/builder/babel-plugin-pdfjs-preprocessor.mjs
+++ b/external/builder/babel-plugin-pdfjs-preprocessor.mjs
@@ -173,6 +173,36 @@ function babelPluginPDFJSPreprocessor(babel, ctx) {
           path.replaceWith(t.importExpression(source));
         }
       },
+      NewExpression(path) {
+        const { node } = path;
+
+        if (
+          t.isIdentifier(node.callee, { name: "URL" }) &&
+          node.arguments.length === 2
+        ) {
+          const [arg1, arg2] = node.arguments;
+
+          if (
+            arg1.type === "StringLiteral" &&
+            arg1.value.endsWith(".wasm") &&
+            arg2.type === "MemberExpression"
+          ) {
+            // This statement is generated by the Emscripten Compiler (emcc),
+            // however we're manually loading wasm-files and we want to ensure
+            // that bundlers will leave it alone; this *must* include Webpack.
+            arg1.leadingComments = [
+              {
+                type: "CommentBlock",
+                value: "webpackIgnore: true",
+              },
+              {
+                type: "CommentBlock",
+                value: "@vite-ignore",
+              },
+            ];
+          }
+        }
+      },
       "BlockStatement|StaticBlock": {
         // Visit node in post-order so that recursive flattening
         // of blocks works correctly.
diff --git a/external/builder/fixtures_babel/ignore-expected.js b/external/builder/fixtures_babel/ignore-expected.js
new file mode 100644
index 000000000..0db4463ee
--- /dev/null
+++ b/external/builder/fixtures_babel/ignore-expected.js
@@ -0,0 +1,4 @@
+const wasmUrl = new URL(
+/*webpackIgnore: true*/
+/*@vite-ignore*/
+"qwerty.wasm", import.meta.url);
diff --git a/external/builder/fixtures_babel/ignore.js b/external/builder/fixtures_babel/ignore.js
new file mode 100644
index 000000000..74371deac
--- /dev/null
+++ b/external/builder/fixtures_babel/ignore.js
@@ -0,0 +1 @@
+const wasmUrl = new URL("qwerty.wasm" , import.meta.url);